AC Milan return to Serie A action in Matchday 6 as they make the relatively short trip to Liguria to take on a struggling Sampdoria side who look set to be in for a long season. The Rossoneri will want to pick up where they left off domestically, having beaten Inter 3-2 in the Derby della Madonnina last time out in Serie A.
Stefano Pioli took his side away to RB Salzburg in midweek as they opened their Champions League campaign. Again, though, they disappointed on the continental stage and only took one point home to Milan with them, with Alexis Saelemaekers equalising after they had fallen behind.
Now, though, all eyes will be on a poor Samp side and Milan will fancy themselves to take maximum points.


Sampdoria v AC Milan: Predicted line-ups
Despite Saelemaekers‘ midweek goal in the Champions League, La Gazzetta dello Sport are reporting that Pioli will return to the XI that served him so well in the Milan Derby last weekend. That means another start for new signing Charles De Ketelaere.
Zlatan Ibrahimovic, Ante Rebic, Rade Krunic, and Alessandro Florenzi remain injured.
Sampdoria are without Simone Trimboli, Andrea Conti and Nicola Murru through injury.
Sampdoria predicted XI v AC Milan (4-1-4-1): Audero; Bereszynski, Ferrari, Colley, Augello; Vieira; Leris, Rincon, Sabiri, Djuricic; Caputo.
AC Milan predicted XI v Sampdoria (4-2-3-1): Maignan; Calabria, Kalulu, Tomori, Hernandez; Tonali, Bennacer; Messia, De Ketelaere, Leao; Giroud.
Sampdoria v AC Milan: When does the Serie A fixture start?
The Serie A Matchday 6 fixture of Sampdoria v AC Milan kicks off at 20:45 CEST – local time in Italy – making it a 19:45 kick-off in the United Kingdom.
In the United States, kick-off in Sampdoria v AC Milan is 14:45 ET or 11:45 PT.
Sampdoria v AC Milan: Where to watch the Serie A fixture?
In the United States, every Serie A game in 2022/23 can be seen on Paramount+, including Sampdoria v AC Milan and the other standout fixtures of Serie A Matchday 6.
In the United Kingdom and Ireland, you can watch Sampdoria v AC Milan on BT Sport 1.