The Giallorossi go into the round of fixtures in fifth place after a late 3-1 win over Udinese last time out, with Jose Mourinho‘s side keen to find consistent form in the run up to Christmas.
Sassuolo had a last-gasp win of their own in Matchday 13, in a thrilling 4-3 victory at Empoli, pulling them five points clear of the Serie A relegation zone.
Sassuolo vs AS Roma: Predicted line-ups
As reported by La Gazzetta dello Sport, Roma are looking to Paulo Dybala to provide the spark in attack alongside Romelu Lukaku, whilst Edoardo Bove could step into midfield should Mourinho opt not to risk captain Lorenzo Pellegrini.
Tammy Abraham and Marash Kumbulla are still long-term absentees, whilst Chris Smalling is not expected to play in part in the match. Centre-back Gianluca Mancini is one booking away from suspension.
Sassuolo duo Mattia Viti and Pedro Obiang will be assessed closer to kick-off after recent injuries, but forward Agustin Alvarez is ruled out.
Ex-Roma men Matias Vina and Gregoire Defrel are expected to feature on the left flank, with Domenico Berardi and Andrea Pinamonti set to provide the goal threat in attack.
Sassuolo predicted XI vs AS Roma (4-2-3-1): Consigli; Toljan, Erlic, Ferrari, Vina; Boloca, Thorstvedt; Berardi, Castillejo, Defrel; Pinamonti
AS Roma predicted XI vs Sassuolo (3-5-2): Rui Patricio; Mancini, Llorente, Ndicka; Karsdorp, Cristante, Paredes, Bove, Spinazzola; Dybala, Lukaku
Serie A: When does Sassuolo vs AS Roma start?
Kick-off in the Serie A Matchday 14 fixture of Sassuolo vs AS Roma is set for 18:00 CET, local time in Italy, on Sunday, December 3.
For viewers in the United Kingdom and Ireland, the game will start at 17:00 GMT. That is 12:00 ET / 09:00 PT in the United States.
Serie A: Where to watch Sassuolo vs AS Roma?
For fans in the United States, Sassuolo vs AS Roma will be on Paramount+ along with other fixtures on Serie A Matchday 14.
Sassuolo vs AS Roma will be shown on TNT Sports 3 in the United Kingdom and Ireland.